Background

Organoids are unique three-dimensional cell cultures in which polarized cells form tiny spheres. Each organoid is a miniature model of the in vivo cellular architecture and is unique to the person who provided the cells to grow the organoid. PBA’s organoids utilize easily accessible cells and do not require induced pluripotency.

Organoids are:

  • Derived from patients who have the disease of interest,
  • Replicate patient-specific characteristics,
  • Grown from progenitor cells that differentiate into target cell types, and
  • Exhibit multi-scale biological function and mimic the in vivo cellular architecture.

 

Organoids Cystic Fibrosis Functional Drug Screening